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KMID : 0359319820220010037
Korean Journal of Veterinary Research
1982 Volume.22 No. 1 p.37 ~ p.52
Histopathologic Studies on the Brain and Lymphoid Organs in Hog Cholera


Abstract
This study was taken to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the necrotic lesion and inclusion body in the lymphoid organs were carried out in the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. Electron microscopic fin dings of the intranuclear inclusion bodies in the reticular cell of spleen and lymph node were also observed in the experimental cases.
The results obtained are as follow,
As the histological findings necrosis of lymphoid organs was observed mainly in the lymph follicle. The necrotic lymphoid organs were found to contain 35.0% in the natural and 37.5% in the experimental
Intranuclear in elusion bodies were found mainly in the reticular cells of lymphoid organ, the epithelium of bronchiole and alevolus, and the vascular endothelium of brain. These inclusion bodies were seen in 40.0% of the natural cases and all of the experiment. The inclusion body was appeared to compose of activated nucleoli and chromatin ganules (interchromatin and perichromatin) by electron microscopy.
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